Active constituents
The active constituents in anise, particularly the terpenoid anethole, are contained in its volatile oil. The volatile oil gives the plant a delightful flavour and has been combined with other less pleasant tasting medicinal herbs to offset their taste. The oil is also antispasmodic, helping to relieve intestinal wind and spasmodic coughs.3 Anise has been combined with cathartic laxatives to help reduce the spasmodic cramping they can cause.4 It may also have modest antiparasitic actions and has been recommended by some practitioners to treat mild intestinal parasite infections.5 Anethole has been documented to have phytoestrogen activity in test tubes and animals;6 the relevance of this to humans is unknown. No clinical trials have been conducted to support any of these uses, though anise is approved for use by the German Commission E for relieving coughs and indigestion.7
References
1. Chopra RN, Chandler AC. Anthelmintics and Their Uses in Medical and Veterinary Practice. Baltimore: Williams & Wilkins Co, 1928:159.
2. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
3. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
4. Mills SY. Out of the Earth: The Essential Book of Herbal Medicine. Middlesex, UK: Viking Arkana, 1991:290
5. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
6. Albert-Puleo M. Fennel and anise as estrogenic agents. J Ethnopharm 1980;2:337–44.
7. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998:82–3.
8. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
9. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998:82–3.
10. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:203–4.
11. Bingel AS, Farnsworth NR. Higher plants as potential sources of galactagogues. Econ Med Plant Res 1994;6:1–54 [review].

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