Anti-oxidants and Free Radicals
Free radicals are highly reactive compounds that are created in the body
during normal metabolic functions or introduced from the environment. Free
radicals are inherently unstable, since they contain “extra” energy.
To reduce their energy load, free radicals react with certain chemicals in the
body, and in the process, interfere with the cells’ ability to function
normally. Anti-oxidants work in a few ways: they may reduce the energy of the free
radical, stop the free radical from forming in the first place, or interrupt an
oxidizing chain reaction to minimise the damage caused by free radicals.
Free radicals are believed to play a role in more than sixty
different health conditions, including the aging process, cancer, and
atherosclerosis.1
Reducing exposure to free radicals and increasing intake of anti-oxidant
nutrients has the potential to reduce the risk of free radical-related health
problems.
Oxygen, although essential to life, is the source of the potentially damaging
free radicals. Free radicals are also found in the environment. Environmental
sources of free radicals include exposure to ionizing radiation (from industry,
sun exposure, cosmic rays, and medical X-rays), ozone and nitrous oxide
(primarily from automobile exhaust), heavy metals (such as mercury, cadmium, and
lead), cigarette smoke (both active and passive), alcohol, unsaturated fat, and
other chemicals and compounds from food, water, and air.
The body produces a fewanti-oxidant enzymes, including superoxide dismutase (SOD),
catalase, and glutathione peroxidase, that neutralize many types of free
radicals. Supplements of these enzymes are available for oral administration.
However, their absorption is probably minimal at best. Supplementing with the
“building blocks” the body requires to make SOD, catalase, and
glutathione peroxidase may be more effective. These building block nutrients
include the minerals manganese, zinc, and
copper for SOD and selenium for
glutathione peroxidase.
In addition to enzymes, many vitamins and minerals act as anti-oxidants in
their own right, such as vitamin C, vitamin
E, beta-carotene, lutein,
lycopene,
vitamin B2, co-Enzyme Q10, and cysteine (an amino acid). Herbs, such as
bilberry,
turmeric (curcumin), grape seed or pine bark extracts, and
ginkgo can also
provide powerful anti-oxidant protection for the body.
Consuming a wide variety of anti-oxidant enzymes, vitamins, minerals, and
herbs may be the best way to provide the body with the most complete protection
against free radical damage.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.