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Policosanol

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Policosanol is a mixture of long-chain alcohols (waxes), including octacosanol, extracted from natural sources.

Where is it found?

The long-chain alcohols found in policosanol are present in many foods of plant origin. Supplemental policosanol is typically extracted from sugar cane or beeswax.

Policosanol has been used in connection with the following condition (refer to the individual health concern for complete information):

Rating Health Concerns
3Stars Intermittent claudication
2Stars High triglycerides
1Star High cholesterol
3Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Policosanol is not an essential nutrient, so no deficiencies are possible.

How much is usually taken?

Most studies have used 5 to 10 mg of policosanol taken twice per day.

Are there any side effects or interactions?

When policosanol is combined with aspirin, an increased blood-thinning effect occurs.1 This suggests that policosanol should not be taken with blood-thinning drugs without the supervision of a doctor.

At the time of writing, there were no well-known drug interactions with policosanol.

References

1. Arruzazabala ML, Valdes S, Mas R, et al. Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol Res 1997;36:293–7.

2007-09-01